Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp84 | Bone development/growth and fracture repair | ECTS2013

Variations in osteotoxic effects of cadmium on femoral bone structure after different routes of exposure

Martiniakova Monika , Chovancova Hana , Omelka Radoslav , Bobonova Ivana , Toman Robert

Cadmium (Cd) is regarded as a risk factor for various bone diseases in humans and experimental animals. To compare effects of different routes of Cd administration on femoral bone structure, ten 4-month-old male Wistar rats (group A) were injected intraperitoneally with a single dose of 2 mg CdCl2/kg body weight and killed 36 h after Cd had been injected. Ten 1-month-old male rats (group B) were dosed with a daily Cd intake of 30 mg CdCl2/l in drinking wa...

ba0003pp43 | Bone development/growth and fracture repair | ECTS2014

Subchronic co-administration to cadmium, diazinon and selenium causes apparent symptoms of osteoporosis in adult male rats

Omelka Radoslav , Chovancova Hana , Bobonova Ivana , Formicki Grzegorz , Toman Robert , Martiniakova Monika

Osteoporosis, as a global public health concern, may be induced by various hazardous substances such as cadmium (Cd) and pesticide diazinon (DZN). Selenium (Se), an essential trace element, can adversely modify bone structure in higher concentrations. The current study was designed to investigate structural changes in femoral bone of adult male rats after simultaneous co-administration to Cd, DZN, and Se. A total of 20 male Wistar rats were randomly divided into two experiment...